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Can a Person Get Mono More Than Once?

Can a person get mono more than once?

Mononucleosis usually is caused by the Epstein-Barr virus (EBV). When someone gets mono, the stays in the body for the rest of that person's life. It can even reappear in the person's saliva (spit) from time to time. But the person probably won't get mono symptoms (like being tired all the time, a sore throat, fever, and loss of appetite) again.

If you have mono symptoms — even if you've had it before — see your doctor. Other illnesses such as strep throat and the flu may cause similar symptoms. Your doctor can make an accurate diagnosis.

*Names have been changed to protect user privacy.

Date reviewed: May 2018